Enhancer of mRNA Decapping protein 4 (EDC4) interacts with replication protein a (RPA) and contributes to Cisplatin resistance in cervical Cancer by alleviating DNA damage

Abstract Background Cervical cancer (CC) is the third most common gynecological malignancy around the world. Cisplatin is an effective drug, but cisplatin resistance is a vital factor limiting the clinical usage of cisplatin. Enhancer of mRNA decapping protein 4 (EDC4) is a known regulator of mRNA d...

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Библиографические подробности
Главные авторы: Xiaoling Wu, Youwen Zhong, Qing Chen, Xin Zhang, Hua Zhang
Формат: Artigo
Язык:Inglês
Опубликовано: BMC 2020-10-01
Серии:Hereditas
Предметы:
Cervical Cancer
Cisplatin resistance
Enhancer of mRNA decapping protein 4 (EDC4)
Replication protein a (RPA)
DNA damage
Online-ссылка:http://link.springer.com/article/10.1186/s41065-020-00154-w
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