Comprehensive routine diagnostic screening to identify predictive mutations, gene amplifications, and microsatellite instability in FFPE tumor material

Abstract Background Sensitive and reliable molecular diagnostics is needed to guide therapeutic decisions for cancer patients. Although less material becomes available for testing, genetic markers are rapidly expanding. Simultaneous detection of predictive markers, including mutations, gene amplific...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Elisabeth M. P. Steeghs, Leonie I. Kroeze, Bastiaan B. J. Tops, Leon C. van Kempen, Arja ter Elst, Annemiek W. M. Kastner-van Raaij, Sandra J. B. Hendriks-Cornelissen, Mandy J. W. Hermsen, Erik A. M. Jansen, Petra M. Nederlof, Ed Schuuring, Marjolijn J. L. Ligtenberg, Astrid Eijkelenboom
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2020-04-01
Serie:BMC Cancer
Soggetti:
Predictive analysis
Next-generation sequencing
Mutation
Gene amplification
Microsatellite instability
FFPE
Accesso online:http://link.springer.com/article/10.1186/s12885-020-06785-6
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi