RAS testing in metastatic colorectal cancer: excellent reproducibility amongst 17 Dutch pathology centers

In 2013 the European Medicine Agency (EMA) restricted the indication for anti-EGFR targeted therapy to metastatic colorectal cancer (mCRC) with a wild-type RAS gene, increasing the need for reliable RAS mutation testing. We evaluated the completeness and reproducibility of RAS-testing in the Netherl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Boleij, Annemarie, Tops, Bastiaan B.J., Rombout, Paul D.M., Dequeker, Elizabeth M., Ligtenberg, Marjolijn J.L., van Krieken, J. Han
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558179/
https://ncbi.nlm.nih.gov/pubmed/25944693
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