MiRNA-192 [corrected] and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma.

Accumulated evidence demonstrated that long non-coding RNAs (lncRNAs) play a pivotal role in tumorigenesis. However, it is still largely unknown how these lncRNAs were regulated by small ncRNAs, such as microRNAs (miRNAs), at the post-transcriptional level. We here use lncRNA HOTTIP as an example to...

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Main Authors: Yunxia Ge, Xiaodan Yan, Yiguang Jin, Xinyu Yang, Xiang Yu, Liqing Zhou, Sichong Han, Qipeng Yuan, Ming Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-12-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC4692503?pdf=render
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