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Functional glycosylation of dystroglycan is crucial for thymocyte development in the mouse.

Alpha-dystroglycan (alpha-DG) is a cell surface receptor providing a molecular link between the extracellular matrix (ECM) and the actin-based cytoskeleton. During its biosynthesis, alpha-DG undergoes specific and unusual O-glycosylation crucial for its function as a high-affinity cellular receptor...

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Detalhes bibliográficos
Main Authors: Li-Ying Liou, Kevin B Walsh, Arineh R Vartanian, Daniel Beltran-Valero de Bernabe, Megan Welch, Kevin P Campbell, Michael B A Oldstone, Stefan Kunz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-03-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2848029?pdf=render
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