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The Mechanism of Ferroptosis and Applications in Tumor Treatment

Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of glutathione peroxidase 4 (GPX4) is characteristic of the ferroptosis process. In recent years, with the in-d...

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Autori principali: Xinyue Lin, Jieyi Ping, Yi Wen, Yan Wu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020-07-01
Serie:Frontiers in Pharmacology
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Accesso online:https://www.frontiersin.org/article/10.3389/fphar.2020.01061/full
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