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Conditional Depletion of Hippocampal Brain-Derived Neurotrophic Factor Exacerbates Neuropathology in a Mouse Model of Alzheimer’s Disease

Damage occurring to noradrenergic neurons in the locus coeruleus (LC) contributes to the evolution of neuroinflammation and neurodegeneration in a variety of conditions and diseases. One cause of LC damage may be loss of neurotrophic support from LC target regions. We tested this hypothesis by condi...

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Detalhes bibliográficos
Main Authors: David J. Braun, Sergey Kalinin, Douglas L. Feinstein
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2017-03-01
Colecção:ASN Neuro
Acesso em linha:https://doi.org/10.1177/1759091417696161
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