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Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose

Rheumatoid arthritis (RA) is a multifactorial autoimmune disease whose main hallmark is inflammation and destruction of the joints. Two cell types within the synovium that play an important role in RA are fibroblast-like synoviocytes (FLS) and macrophages. The latter innate immune cells show a high...

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Main Authors: Lisa Deloch, Jana Fuchs, Michael Rückert, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Limited 2019-01-01
Series:Journal of Immunology Research
Acceso en liña:http://dx.doi.org/10.1155/2019/3161750
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