Delayed administration of suramin attenuates peritoneal fibrosis in rats

Abstract Background Peritoneal fibrosis is the most common complication of peritoneal dialysis, but there is currently no effective treatment. We previously reported that suramin pretreatment prevents the development of peritoneal fibrosis in a rat model of peritoneal fibrosis induced by chlorhexidi...

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Auteurs principaux: Chongxiang Xiong, Na Liu, Xiaofei Shao, Sairah Sharif, Hequn Zou, Shougang Zhuang
Format: Artigo
Langue:Inglês
Publié: BMC 2019-11-01
Collection:BMC Nephrology
Sujets:
Suramin
Peritoneal fibrosis
Epidermal growth factor receptor
Signal transducers, activator of transcription 3
Extracellular signal-regulated kinases ½
Accès en ligne:http://link.springer.com/article/10.1186/s12882-019-1597-2
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