Delayed administration of suramin attenuates peritoneal fibrosis in rats

Abstract Background Peritoneal fibrosis is the most common complication of peritoneal dialysis, but there is currently no effective treatment. We previously reported that suramin pretreatment prevents the development of peritoneal fibrosis in a rat model of peritoneal fibrosis induced by chlorhexidi...

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Autors principals: Chongxiang Xiong, Na Liu, Xiaofei Shao, Sairah Sharif, Hequn Zou, Shougang Zhuang
Format: Artigo
Idioma:Inglês
Publicat: BMC 2019-11-01
Col·lecció:BMC Nephrology
Matèries:
Suramin
Peritoneal fibrosis
Epidermal growth factor receptor
Signal transducers, activator of transcription 3
Extracellular signal-regulated kinases ½
Accés en línia:http://link.springer.com/article/10.1186/s12882-019-1597-2
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