Delayed administration of suramin attenuates peritoneal fibrosis in rats

Abstract Background Peritoneal fibrosis is the most common complication of peritoneal dialysis, but there is currently no effective treatment. We previously reported that suramin pretreatment prevents the development of peritoneal fibrosis in a rat model of peritoneal fibrosis induced by chlorhexidi...

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Autori principali: Chongxiang Xiong, Na Liu, Xiaofei Shao, Sairah Sharif, Hequn Zou, Shougang Zhuang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2019-11-01
Serie:BMC Nephrology
Soggetti:
Suramin
Peritoneal fibrosis
Epidermal growth factor receptor
Signal transducers, activator of transcription 3
Extracellular signal-regulated kinases ½
Accesso online:http://link.springer.com/article/10.1186/s12882-019-1597-2
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