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Radical SAM-dependent ether crosslink in daropeptide biosynthesis
Darobactin is a ribosomally synthesized and post-translationally modified peptide featuring a unique scaffold and potent activity against Gram-negative bacteria. Here, the authors identify darobactin synthase DarE as responsible for the bicyclic scaffold formation and propose the name daropeptide fo...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Portfolio
2022-04-01
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Colecção: | Nature Communications |
Acesso em linha: | https://doi.org/10.1038/s41467-022-30084-2 |
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