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Pharmacogenetic modulation of orexin neurons alters sleep/wakefulness states in mice.

Hypothalamic neurons expressing neuropeptide orexins are critically involved in the control of sleep and wakefulness. Although the activity of orexin neurons is thought to be influenced by various neuronal input as well as humoral factors, the direct consequences of changes in the activity of these...

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Autori principali: Koh Sasaki, Mika Suzuki, Michihiro Mieda, Natsuko Tsujino, Bryan Roth, Takeshi Sakurai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2011-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3103553?pdf=render
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