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Biomarker repurposing: Therapeutic drug monitoring of serum theophylline offers a potential diagnostic biomarker of Parkinson's disease.

Caffeine has been considered a neuroprotective agent against Parkinson's disease (PD). Recent metabolomic analysis showed that levels of caffeine and its metabolites were decreased in sera from patients with PD compared with those from healthy controls. We focused on theophylline, which is one...

詳細記述

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書誌詳細
主要な著者: Takuma Ohmichi, Takashi Kasai, Tadashi Kosaka, Keisuke Shikata, Harutsugu Tatebe, Ryotaro Ishii, Makiko Shinomoto, Toshiki Mizuno, Takahiko Tokuda
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2018-01-01
シリーズ:PLoS ONE
オンライン・アクセス:http://europepmc.org/articles/PMC6059449?pdf=render
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