Insertions and Duplications in the Polyproline Region of the Hepatitis E Virus

Recombinant strains of hepatitis E virus (HEV) with insertions of human genomic fragments or HEV sequence duplications in the sequence encoding the polyproline region (PPR) were previously described in chronically infected patients. Such genomic rearrangements confer a replicative advantage in vitro...

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Detaylı Bibliyografya
Asıl Yazarlar: Sébastien Lhomme, Florence Nicot, Nicolas Jeanne, Chloé Dimeglio, Alain Roulet, Caroline Lefebvre, Romain Carcenac, Maxime Manno, Martine Dubois, Jean-Marie Peron, Laurent Alric, Nassim Kamar, Florence Abravanel, Jacques Izopet
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020-01-01
Seri Bilgileri:Frontiers in Microbiology
Konular:
hepatitis E virus
polyproline region
genomic rearrangement
virus-host recombinant variants
virus-virus recombinant variants
Online Erişim:https://www.frontiersin.org/article/10.3389/fmicb.2020.00001/full
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