Influence of Polyproline Region and Macro Domain Genetic Heterogeneity on HEV Persistence in Immunocompromised Patients

Hepatitis E virus (HEV) can chronically infect immunocompromised patients. The polyproline region (PPR) and the macro domain of ORF1 protein may modulate virus production and/or the host immune response. We investigated the association between the genetic heterogeneity of HEV quasispecies in ORF1 an...

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Bibliographic Details
Published in:J Infect Dis
Main Authors: Lhomme, Sebastien, Garrouste, Cyril, Kamar, Nassim, Saune, Karine, Abravanel, Florence, Mansuy, Jean-Michel, Dubois, Martine, Rostaing, Lionel, Izopet, Jacques
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7107305/
https://ncbi.nlm.nih.gov/pubmed/23964111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit438
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