Glutathione Induced Immune-Stimulatory Activity by Promoting M1-Like Macrophages Polarization via Potential ROS Scavenging Capacity

The present study investigated the immunomodulatory activity of reduced glutathione (GSH) by assessment of the macrophage polarization (MP)-mediated immune response in RAW 264.7 cells. Furthermore, we identified the signal pathway associated with immune regulation by GSH. The expressions of MP-assoc...

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Detalhes bibliográficos
Main Authors: Da Hye Kwon, Hyesook Lee, Cheol Park, Su-Hyun Hong, Sang Hoon Hong, Gi-Young Kim, Hee-Jae Cha, Suhkmann Kim, Heui-Soo Kim, Hye-Jin Hwang, Yung Hyun Choi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-09-01
Colecção:Antioxidants
Assuntos:
glutathione
reactive oxygen species
heme oxygenase-1
immune response
macrophage polarization
inflammatory cytokines
antioxidant
Acesso em linha:https://www.mdpi.com/2076-3921/8/9/413
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