Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis

Transthyretin (TTR) amyloidoses (ATTR amyloidosis) are diseases associated with transthyretin (TTR) misfolding, aggregation and extracellular deposition in tissues as amyloid. Clinical manifestations of the disease are variable and include mainly polyneuropathy and/or cardiomyopathy. The reasons why...

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Hauptverfasser: Nelson Ferreira, Maria João Saraiva, Maria Rosário Almeida
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2019-03-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
curcumin
transthyretin
amyloidosis
protein aggregation
protein misfolding
drug discovery
Online Zugang:http://www.mdpi.com/1422-0067/20/6/1287
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