Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis

Transthyretin (TTR) amyloidoses (ATTR amyloidosis) are diseases associated with transthyretin (TTR) misfolding, aggregation and extracellular deposition in tissues as amyloid. Clinical manifestations of the disease are variable and include mainly polyneuropathy and/or cardiomyopathy. The reasons why...

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Detalhes bibliográficos
Main Authors: Nelson Ferreira, Maria João Saraiva, Maria Rosário Almeida
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-03-01
Colecção:International Journal of Molecular Sciences
Assuntos:
curcumin
transthyretin
amyloidosis
protein aggregation
protein misfolding
drug discovery
Acesso em linha:http://www.mdpi.com/1422-0067/20/6/1287
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