Ammonia as a potential neurotoxic factor in Alzheimer disease

Ammonia is known to be a potent neurotoxin that causes severe negative effects on the central nervous system. Excessive ammonia levels have been detected in the brain of patients with neurological disorders such as Alzheimer disease (AD). Therefore, ammonia could be a factor contributing to the prog...

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Main Authors: Aida Adlimoghaddam, Mohammad Golam Sabbir, Benedict C Albensi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016-08-01
Serija:Frontiers in Molecular Neuroscience
Teme:
Alzheimer Disease
Ammonia
Energy Metabolism
neurotransmission
Mitochondrial dysfunction
Toxicity
Online dostop:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00057/full
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