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A protein-conjugate approach to develop a monoclonal antibody-based antigen detection test for the diagnosis of human brucellosis.

Human brucellosis is most commonly diagnosed by serology based on agglutination of fixed Brucella abortus as antigen. Nucleic acid amplification techniques have not proven capable of reproducibly and sensitively demonstrating the presence of Brucella DNA in clinical specimens. We sought to optimize...

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書誌詳細
主要な著者: Kailash P Patra, Mayuko Saito, Vidya L Atluri, Hortensia G Rolán, Briana Young, Tobias Kerrinnes, Henk Smits, Jessica N Ricaldi, Eduardo Gotuzzo, Robert H Gilman, Renee M Tsolis, Joseph M Vinetz
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2014-06-01
シリーズ:PLoS Neglected Tropical Diseases
オンライン・アクセス:http://europepmc.org/articles/PMC4046965?pdf=render
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