Tau Protein Modulates Perineuronal Extracellular Matrix Expression in the TauP301L-<i>acan</i> Mouse Model

Tau mutations promote the formation of tau oligomers and filaments, which are neuropathological signs of several tau-associated dementias. Types of neurons in the CNS are spared of tau pathology and are surrounded by a specialized form of extracellular matrix; called perineuronal nets (PNs). Aggreca...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Sophie Schmidt, Max Holzer, Thomas Arendt, Mandy Sonntag, Markus Morawski
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2022-03-01
Series:Biomolecules
Assuntos:
perineuronal nets
aggrecan
tau pathology
neuroprotection
P301L
sulfated proteoglycans
Acceso en liña:https://www.mdpi.com/2218-273X/12/4/505
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares