Necrostatin-1 Ameliorates Peripheral Nerve Injury-Induced Neuropathic Pain by Inhibiting the RIP1/RIP3 Pathway

Necrostatin-1 is an inhibitor of necroptosis, a form of programmed cell death that has been reported to be involved in various neurological diseases. Presently, the role of necroptosis in neuropathic pain induced by peripheral nerve injury is still unclear. This study was focused on investigating th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ying-Xia Liang, Nan-Nan Wang, Zhi-Yu Zhang, Zhao-Dong Juan, Can Zhang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019-05-01
Cyfres:Frontiers in Cellular Neuroscience
Pynciau:
necroptosis
necrostatin-1
neuropathic pain
inflammatory cytokines
hyperalgesia
peripheral nerve injury
Mynediad Ar-lein:https://www.frontiersin.org/article/10.3389/fncel.2019.00211/full
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