A cross-omics integrative study of metabolic signatures of chronic obstructive pulmonary disease

Abstract Background Chronic obstructive pulmonary disease (COPD) is a common lung disorder characterized by persistent and progressive airflow limitation as well as systemic changes. Metabolic changes in blood may help detect COPD in an earlier stage and predict prognosis. Methods We conducted a com...

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Main Authors: Ivana Prokić, Lies Lahousse, Maaike de Vries, Jun Liu, Marita Kalaoja, Judith M. Vonk, Diana A. van der Plaat, Cleo C. van Diemen, Ashley van der Spek, Alexandra Zhernakova, Jingyuan Fu, Mohsen Ghanbari, Mika Ala-Korpela, Johannes Kettunen, Aki S. Havulinna, Markus Perola, Veikko Salomaa, Lars Lind, Johan Ärnlöv, Bruno H. C. Stricker, Guy G. Brusselle, H. Marike Boezen, Cornelia M. van Duijn, Najaf Amin
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2020-07-01
Series:BMC Pulmonary Medicine
Assuntos:
COPD
Metabolomics
Mendelian randomization
Glycoprotein acetyls
Biomarkers
Acceso en liña:http://link.springer.com/article/10.1186/s12890-020-01222-7
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