Alterations in Cellular Iron Metabolism Provide More Therapeutic Opportunities for Cancer

Iron is an essential element for the growth and proliferation of cells. Cellular iron uptake, storage, utilization and export are tightly regulated to maintain iron homeostasis. However, cellular iron metabolism pathways are disturbed in most cancer cells. To maintain rapid growth and proliferation,...

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Bibliografiske detaljer
Main Authors: Liangfu Zhou, Bin Zhao, Lixiu Zhang, Shenghang Wang, Dandan Dong, Huanhuan Lv, Peng Shang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2018-05-01
Serier:International Journal of Molecular Sciences
Fag:
iron metabolism
cancer
iron chelators
targeted therapy
redox homeostasis
Online adgang:http://www.mdpi.com/1422-0067/19/5/1545
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