Identification of Synergistic Drug Combinations to Target KRAS-Driven Chemoradioresistant Cancers Utilizing Tumoroid Models of Colorectal Adenocarcinoma and Recurrent Glioblastoma

Treatment resistance is observed in all advanced cancers. Colorectal cancer (CRC) presenting as colorectal adenocarcinoma (COAD) is the second leading cause of cancer deaths worldwide. Multimodality treatment includes surgery, chemotherapy, and targeted therapies with selective utilization of immuno...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kshama Gupta, Jeremy C. Jones, Virginea De Araujo Farias, Yuri Mackeyev, Pankaj K. Singh, Alfredo Quiñones-Hinojosa, Sunil Krishnan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2022-05-01
Cyfres:Frontiers in Oncology
Pynciau:
KRAS
DDR1
BCR-ABL1
COAD
GBM
chemoradioresistance
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fonc.2022.840241/full
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg