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Optimization of the antimicrobial peptide Bac7 by deep mutational scanning
Abstract Background Intracellularly active antimicrobial peptides are promising candidates for the development of antibiotics for human applications. However, drug development using peptides is challenging as, owing to their large size, an enormous sequence space is spanned. We built a high-throughp...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
BMC
2022-05-01
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Σειρά: | BMC Biology |
Θέματα: | |
Διαθέσιμο Online: | https://doi.org/10.1186/s12915-022-01304-4 |
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