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Improving the estimation of celiac disease sibling risk by non-HLA genes.

Celiac Disease (CD) is a polygenic trait, and HLA genes explain less than half of the genetic variation. Through large GWAs more than 40 associated non-HLA genes were identified, but they give a small contribution to the heritability of the disease. The aim of this study is to improve the estimate o...

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Detalhes bibliográficos
Main Authors: Valentina Izzo, Michele Pinelli, Nadia Tinto, Maria Valeria Esposito, Arturo Cola, Maria Pia Sperandeo, Francesca Tucci, Sergio Cocozza, Luigi Greco, Lucia Sacchetti
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3210127?pdf=render
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