DNA Polymerases λ and β: The Double-Edged Swords of DNA Repair

DNA is constantly exposed to both endogenous and exogenous damages. More than 10,000 DNA modifications are induced every day in each cell’s genome. Maintenance of the integrity of the genome is accomplished by several DNA repair systems. The core enzymes for these pathways are the DNA polymerases. O...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Elisa Mentegari, Miroslava Kissova, Laura Bavagnoli, Giovanni Maga, Emmanuele Crespan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2016-08-01
Cyfres:Genes
Pynciau:
DNA polymerases
DNA repair
translesion synthesis
cancer chemotherapy
mutagenesis
Mynediad Ar-lein:http://www.mdpi.com/2073-4425/7/9/57
Tagiau: Ychwanegu Tag
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