α-Chaconine and α-Solanine Inhibit RL95-2 Endometrium Cancer Cell Proliferation by Reducing Expression of Akt (Ser473) and ERα (Ser167)

The aim of this study is to investigate the potential inhibitory effect of α-chaconine and α-solanine on RL95-2 estrogen receptor (ER) positive human endometrial cancer cell line and to identify the effect of these glycoalkaloids on the Akt signaling and ERα. The cell p...

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Autori principali: Ayşe Kübra Karaboğa Arslan, Mükerrem Betül Yerer
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2018-05-01
Serie:Nutrients
Soggetti:
α-chaconine
α-solanine
Solanum tuberosum L.
API-1
MPP dihydrochloride
RL95-2
endometrium cancer
steroidal glycoalkaloids
Akt
ERα
Accesso online:http://www.mdpi.com/2072-6643/10/6/672
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