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Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis

The epithelial mesenchymal transition (EMT) is important in the metastatic spread of cancer cells. Here, the authors show that the EMT transcription factor, ZEB1, can modify estrogen receptor α during EMT and facilitate the migration of breast cancer cells to the bone

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書誌詳細
主要な著者: Nastaran Mohammadi Ghahhari, Magdalena K. Sznurkowska, Nicolas Hulo, Lilia Bernasconi, Nicola Aceto, Didier Picard
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2022-04-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-022-29723-5
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