Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis

The epithelial mesenchymal transition (EMT) is important in the metastatic spread of cancer cells. Here, the authors show that the EMT transcription factor, ZEB1, can modify estrogen receptor α during EMT and facilitate the migration of breast cancer cells to the bone

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Autores principales: Nastaran Mohammadi Ghahhari, Magdalena K. Sznurkowska, Nicolas Hulo, Lilia Bernasconi, Nicola Aceto, Didier Picard
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2022-04-01
Colección:Nature Communications
Acceso en línea:https://doi.org/10.1038/s41467-022-29723-5
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