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Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis
The epithelial mesenchymal transition (EMT) is important in the metastatic spread of cancer cells. Here, the authors show that the EMT transcription factor, ZEB1, can modify estrogen receptor α during EMT and facilitate the migration of breast cancer cells to the bone
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Nature Portfolio
2022-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-29723-5 |
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