Distinct clinical and somatic mutational features of breast tumors with high-, low-, or non-expressing human epidermal growth factor receptor 2 status

Abstract Background HER2-low breast cancers were reported to have distinct clinicopathological characteristics from HER2-zero; however, the difference in their genetic features remains unclear. This study investigated the clinical and molecular features of breast tumors according to HER2 status. Met...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guochun Zhang, Chongyang Ren, Cheukfai Li, Yulei Wang, Bo Chen, Lingzhu Wen, Minghan Jia, Kai Li, Hsiaopei Mok, Li Cao, Xiaoqing Chen, Jiali Lin, Guangnan Wei, Yingzhi Li, Yuchen Zhang, Charles M. Balch, Ning Liao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2022-04-01
Saila:BMC Medicine
Gaiak:
Breast cancer
Human epidermal growth factor receptor 2 (HER2)
Genomic alteration
HER2-low
Next-generation sequencing (NGS)
Targeted therapy
Sarrera elektronikoa:https://doi.org/10.1186/s12916-022-02346-9
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