Distinct clinical and somatic mutational features of breast tumors with high-, low-, or non-expressing human epidermal growth factor receptor 2 status

Abstract Background HER2-low breast cancers were reported to have distinct clinicopathological characteristics from HER2-zero; however, the difference in their genetic features remains unclear. This study investigated the clinical and molecular features of breast tumors according to HER2 status. Met...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Guochun Zhang, Chongyang Ren, Cheukfai Li, Yulei Wang, Bo Chen, Lingzhu Wen, Minghan Jia, Kai Li, Hsiaopei Mok, Li Cao, Xiaoqing Chen, Jiali Lin, Guangnan Wei, Yingzhi Li, Yuchen Zhang, Charles M. Balch, Ning Liao
Format: Artigo
Idioma:Inglês
Publicat: BMC 2022-04-01
Col·lecció:BMC Medicine
Matèries:
Breast cancer
Human epidermal growth factor receptor 2 (HER2)
Genomic alteration
HER2-low
Next-generation sequencing (NGS)
Targeted therapy
Accés en línia:https://doi.org/10.1186/s12916-022-02346-9
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars