Extracellular Sortilin Proteopathy Relative to β-Amyloid and Tau in Aged and Alzheimer’s Disease Human Brains

Amyloid plaques and neurofibrillary tangles (NFTs) are hallmark lesions of Alzheimer’s disease (AD) related to β-amyloid (Aβ) deposition and intraneuronal phosphorylated tau (pTau) accumulation. Sortilin C-terminal fragments (shortened as “sorfra”) can deposit as senile plaque-like lesions within AD...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tian Tu, Juan Jiang, Qi-Lei Zhang, Lily Wan, Ya-Nan Li, Aihua Pan, Jim Manavis, Xiao-Xin Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-05-01
Colecção:Frontiers in Aging Neuroscience
Assuntos:
ABC score
brain banking
dementia
neurodegeneration
neuritic plaque
Vps10p
Acesso em linha:https://www.frontiersin.org/article/10.3389/fnagi.2020.00093/full
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados