Linezolid Administration to Critically Ill Patients: Intermittent or Continuous Infusion? A Systematic Literature Search and Review

A judicious antibiotic therapy is one of the challenges in the therapy of critically ill patients with sepsis and septic shock. The pathophysiological changes in these patients significantly alter the antibiotic pharmacokinetics (PK) and pharmacodynamics (PD) with important consequences in reaching...

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Detalhes bibliográficos
Main Authors: Ligia-Ancuta Hui, Constantin Bodolea, Laurian Vlase, Elisabeta Ioana Hiriscau, Adina Popa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-03-01
Colecção:Antibiotics
Assuntos:
linezolid
continuous infusion
intermittent infusion
critically ill patients
pharmacokinetics
pharmacodynamics
Acesso em linha:https://www.mdpi.com/2079-6382/11/4/436
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