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Pathway-based screening strategy for multitarget inhibitors of diverse proteins in metabolic pathways.
Many virtual screening methods have been developed for identifying single-target inhibitors based on the strategy of "one-disease, one-target, one-drug". The hit rates of these methods are often low because they cannot capture the features that play key roles in the biological functions of...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science (PLoS)
2013-01-01
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| Serie: | PLoS Computational Biology |
| Länkar: | http://europepmc.org/articles/PMC3701698?pdf=render |
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