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Pathway-based Screening Strategy for Multitarget Inhibitors of Diverse Proteins in Metabolic Pathways
Many virtual screening methods have been developed for identifying single-target inhibitors based on the strategy of “one–disease, one–target, one–drug”. The hit rates of these methods are often low because they cannot capture the features that play key roles in the biological functions of the targe...
সংরক্ষণ করুন:
প্রধান লেখক: | , , , , |
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বিন্যাস: | Artigo |
ভাষা: | Inglês |
প্রকাশিত: |
Public Library of Science
2013
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বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701698/ https://ncbi.nlm.nih.gov/pubmed/23861662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003127 |
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