Performance of International AIDS Vaccine Initiative African clinical research laboratories in standardised ELISpot and peripheral blood mononuclear cell processing in support of HIV vaccine clinical trials

Background: Standardisation of procedures for performing cellular functional assays across laboratories participating in multicentre clinical trials is key for generating comparable and reliable data. Objective: This article describes the performance of accredited laboratories in Africa and Europe...

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Main Authors: Robert K. Langat, Bashir Farah, Jackton Indangasi, Simon Ogola, Gloria Omosa-Manyonyi, Omu Anzala, Jean Bizimana, Emmanuel Tekirya, Caroline Ngetsa, Moses Silwamba, Enoch Muyanja, Paramesh Chetty, Maureen Jangano, Nancy Hills, Jill Gilmour, Len Dally, Josephine H. Cox, Peter Hayes
Formato: Artigo
Idioma:Inglês
Publicado em: AOSIS 2021-02-01
Colecção:African Journal of Laboratory Medicine
Assuntos:
pbmc processing
peripheral blood mononuclear cells
elispot
clinical trials
good clinical laboratory practice
proficiency testing.
Acesso em linha:https://ajlmonline.org/index.php/ajlm/article/view/1056
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