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Sequential Hepatogenic Transdifferentiation of Adipose Tissue-Derived Stem Cells: Relevance of Different Extracellular Signaling Molecules, Transcription Factors Involved, and Expression of New Key Marker Genes

Adipose tissue contains a mesenchymal stem cell (MSC) population known as adipose-derived stem cells (ASCs) capable of differentiating into different cell types. Our aim was to induce hepatic transdifferentiation of ASCs by sequential exposure to several combinations of cytokines, growth factors, an...

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Detalhes bibliográficos
Main Authors: A. Bonora-Centelles, R. Jover, V. Mirabet, A. Lahoz, F. Carbonell, J. V. Castell, M. J. Gómez-Lechón
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publishing 2009-12-01
Colecção:Cell Transplantation
Acesso em linha:https://doi.org/10.3727/096368909X12483162197321
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