Enhanced Hepatogenic Transdifferentiation of Human Adipose Tissue Mesenchymal Stem Cells by Gene Engineering with Oct4 and Sox2

Adipose tissue mesenchymal stem cells (ATMSCs) represent an attractive tool for the establishment of a successful stem cell-based therapy in the field of liver regeneration medicine. ATMSCs overexpressing Oct4 and Sox2 (Oct4/Sox2-ATMSCs) showed enhanced proliferation and multipotency. Hence, we hypo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Han, Sei-Myoung, Coh, Ye-Rin, Ahn, Jin-Ok, Jang, Goo, Yum, Soo Young, Kang, Sung-Keun, Lee, Hee-Woo, Youn, Hwa-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376765/
https://ncbi.nlm.nih.gov/pubmed/25815812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108874
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