5-Fluorouracil and irinotecan (SN-38) have limited impact on colon microbial functionality and composition in vitro

Gastrointestinal mucositis is a debilitating side effect of chemotherapy treatment, with currently no treatment available. As changes in microbial composition have been reported upon chemotherapy treatment in vivo, it is thought that gut microbiota dysbiosis contribute to the mucositis etiology. Yet...

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Main Authors: Eline Vanlancker, Barbara Vanhoecke, Andrea Stringer, Tom Van de Wiele
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2017-11-01
Serier:PeerJ
Fag:
Irinotecan
Chemotherapy
Colon microbiota
5-Fluorouracil
Community analysis
Gut
Online adgang:https://peerj.com/articles/4017.pdf
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