5-Fluorouracil and irinotecan (SN-38) have limited impact on colon microbial functionality and composition in vitro

Gastrointestinal mucositis is a debilitating side effect of chemotherapy treatment, with currently no treatment available. As changes in microbial composition have been reported upon chemotherapy treatment in vivo, it is thought that gut microbiota dysbiosis contribute to the mucositis etiology. Yet...

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Detalhes bibliográficos
Main Authors: Eline Vanlancker, Barbara Vanhoecke, Andrea Stringer, Tom Van de Wiele
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2017-11-01
Colecção:PeerJ
Assuntos:
Irinotecan
Chemotherapy
Colon microbiota
5-Fluorouracil
Community analysis
Gut
Acesso em linha:https://peerj.com/articles/4017.pdf
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