Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival

Purinergic signaling regulates important physiological processes and the homeostatic response to stress in the cochlea via extracellular nucleosides (adenosine) and nucleotides (ATP, UTP). Using a previously established organotypic culture model, the current study investigated the effect of purinerg...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Shelly C. Y. Lin, Peter R. Thorne, Gary D. Housley, Srdjan M. Vlajkovic
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019-05-01
Reeks:Frontiers in Cellular Neuroscience
Onderwerpen:
aminoglycoside ototoxicity
cochlear explant
sensory hair cells
adenosine
ATP
P1 receptor
Online toegang:https://www.frontiersin.org/article/10.3389/fncel.2019.00207/full
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items