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Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival

Purinergic signaling regulates important physiological processes and the homeostatic response to stress in the cochlea via extracellular nucleosides (adenosine) and nucleotides (ATP, UTP). Using a previously established organotypic culture model, the current study investigated the effect of purinerg...

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Bibliografische gegevens
Gepubliceerd in:Front Cell Neurosci
Hoofdauteurs: Lin, Shelly C. Y., Thorne, Peter R., Housley, Gary D., Vlajkovic, Srdjan M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529511/
https://ncbi.nlm.nih.gov/pubmed/31156393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00207
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