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Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival

Purinergic signaling regulates important physiological processes and the homeostatic response to stress in the cochlea via extracellular nucleosides (adenosine) and nucleotides (ATP, UTP). Using a previously established organotypic culture model, the current study investigated the effect of purinerg...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Lin, Shelly C. Y., Thorne, Peter R., Housley, Gary D., Vlajkovic, Srdjan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529511/
https://ncbi.nlm.nih.gov/pubmed/31156393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00207
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