Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival

Purinergic signaling regulates important physiological processes and the homeostatic response to stress in the cochlea via extracellular nucleosides (adenosine) and nucleotides (ATP, UTP). Using a previously established organotypic culture model, the current study investigated the effect of purinerg...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Shelly C. Y. Lin, Peter R. Thorne, Gary D. Housley, Srdjan M. Vlajkovic
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019-05-01
Col·lecció:Frontiers in Cellular Neuroscience
Matèries:
aminoglycoside ototoxicity
cochlear explant
sensory hair cells
adenosine
ATP
P1 receptor
Accés en línia:https://www.frontiersin.org/article/10.3389/fncel.2019.00207/full
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars