2-Hydroxymelatonin, a Predominant Hydroxylated Melatonin Metabolite in Plants, Shows Antitumor Activity against Human Colorectal Cancer Cells

2-Hydroxymelatonin is a predominant hydroxylated melatonin metabolite in plants. To investigate whether it has potent cytotoxic effects on colorectal cancer cells, four colorectal cancer cell lines, Caco2, HCT116, DLD1, and CT26, were treated with 2-hydroxymelatonin and melatonin. 2-Hydroxymelatonin...

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Detalhes bibliográficos
Main Authors: Yi Yang, Rui Zhou, So-Yeon Park, Kyoungwhan Back, Woo Kyun Bae, Kyung Keun Kim, Hangun Kim
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2017-03-01
Colecção:Molecules
Assuntos:
melatonin
metabolite
hydroxymelatonin
antitumor
colorectal cancer
Acesso em linha:http://www.mdpi.com/1420-3049/22/3/453
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