Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

Abstract Background The tumor necrosis factor (TNF) superfamily cytokine TNF-like protein 1A (TL1A) and its receptor DR3 are essential for diverse animal models of autoimmune disease and may be pathogenic in rheumatoid arthritis (RA). However, the relationship of TL1A to disease duration, activity,...

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Main Authors: Yun-Jeong Song, In Ah. Choi, Françoise Meylan, M. Kristen Demoruelle, Taylor Farley, Arianne C. Richard, Eric Hawley, John Botson, Yoo Jin Hong, Eun Young Lee, Sabina R. Mian, Bartlett C. Hamilton, Geoffrey M. Thiele, Ted R. Mikuls, Naveen Gara, Chris D. Ward, Sarah Lamberth, Kevin D. Deane, Theo Heller, Michael M. Ward, David M. Lee, Thi-Sau Migone, William Stohl, James R. O’Dell, Jill M. Norris, V. Michael Holers, Peter Gregersen, Yeong-Wook Song, Richard M. Siegel
Format: Artigo
Language:Inglês
Published: BMC 2020-05-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Cytokines
Tumor necrosis factor-like cytokine 1A
TNFSF15
Collagen-induced arthritis
Online Access:http://link.springer.com/article/10.1186/s13075-020-02198-9
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