Mapping the Complement Factor H-Related Protein 1 (CFHR1):C3b/C3d Interactions.

Por Jonathan P Hannan, Jennifer Laskowski, Joshua M Thurman, Gregory S Hageman, V Michael Holers
Publicado em 2016-01-01

Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice

Por Sidonia Mihai, Sidonia Mihai, Misa Hirose, Yi Wang, Joshua M. Thurman, V. Michael Holers, B. Paul Morgan, Jörg Köhl, Jörg Köhl, Detlef Zillikens, Ralf J. Ludwig, Falk Nimmerjahn
Publicado em 2018-03-01

C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Ar...

Por Nirmal K. Banda, Stephen Tomlinson, Robert I. Scheinman, Nhu Ho, Nhu Ho, Joseline Ramos Ramirez, Gaurav Mehta, Guankui Wang, Vivian Pham Vu, Dmitri Simberg, Liudmila Kulik, V. Michael Holers
Publicado em 2020-10-01

Key Components of the Complement Lectin Pathway Are Not Only Required for the Development of Inflammatory Arthritis but Also Regulate the Transcription of Factor D

Por V. Michael Holers, Anna Borodovsky, Robert I. Scheinman, Nhu Ho, Joseline Ramos Ramirez, József Dobó, Péter Gál, Jared Lindenberger, Annette G. Hansen, Dhruv Desai, Rasmus Pihl, Steffen Thiel, Nirmal K. Banda
Publicado em 2020-02-01

Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis.

Por Jeremy Sokolove, Reuven Bromberg, Kevin D Deane, Lauren J Lahey, Lezlie A Derber, Piyanka E Chandra, Jess D Edison, William R Gilliland, Robert J Tibshirani, Jill M Norris, V Michael Holers, William H Robinson
Publicado em 2012-01-01

Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

Por Yun-Jeong Song, In Ah. Choi, Françoise Meylan, M. Kristen Demoruelle, Taylor Farley, Arianne C. Richard, Eric Hawley, John Botson, Yoo Jin Hong, Eun Young Lee, Sabina R. Mian, Bartlett C. Hamilton, Geoffrey M. Thiele, Ted R. Mikuls, Naveen Gara, Chris D. Ward, Sarah Lamberth, Kevin D. Deane, Theo Heller, Michael M. Ward, David M. Lee, Thi-Sau Migone, William Stohl, James R. O’Dell, Jill M. Norris, V. Michael Holers, Peter Gregersen, Yeong-Wook Song, Richard M. Siegel
Publicado em 2020-05-01