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High pressure-induced mtDNA alterations in retinal ganglion cells and subsequent apoptosis
Purpose: Our previous study indicated that mitochondrial DNA (mtDNA) damage and mutations are crucial to the progressive loss of retinal ganglion cells (RGCs) in a glaucomatous rat model. In this study, we examined whether high pressure could directly cause mtDNA alterations and whether the latter c...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2016-11-01
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| Col·lecció: | Frontiers in Cellular Neuroscience |
| Matèries: | |
| Accés en línia: | http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00254/full |
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